Welcome to Ebrahimkhani Lab for Synthetic Biology and Regenerative Medicine
Our research combines systems and synthetic biology-based approaches to program development of a single induced pluripotent stem cell across the developmental trajectories and towards human fetal and adult designer liver organoids. We establish human organogenesis in a dish, develop technologies to control those processes and decode principle of our tissue development and regeneration. Our vision is to advance regenerative medicine through integrating systems and synthetic biology.
Key words: Synthetic Niche, Human Liver Organoids, Designer Tissues, Engineering Morphogenesis

​For more news, please visit: http://www.ebrahimkhanilab.com/news.html ​
Recent News:

May 2020- Mo was selected as an awardee of Pitt's Pain Research Challenge 2020 for CRISPR-epigenetic therapeutics for pain management.
 
May 2020- Jeremy & Ryan published their pre-print on genetic guided engineering of human liver organoids.
 
January 2020- We published our paper on CRISPR-based synthetic TFs in Cell Systems.
 
October 2019- Our labs moved to Pittsburgh Liver Center and Department of Pathology!

July 2019- We got awarded an RO1 for developing a synthetic liver niche! with many exciting applications.

Oct 2018- We got awarded a UO1 grant with Kiani lab to develop a multicellular liver platform on a chip for CRISPR testing.

July 2018- We got awarded an RO1 together with Kiani lab at ASU to develop novel technologies for genetic circuit engineering with a set of applications in vivo.

Read in Trends in Biotechnology our new paper about engineering morphogenesis!
http://www.cell.com/trends/biotechnology/fulltext/S0167-7799(17)30301-3
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Read in Cell Systems Voices : How we think about "Circuit Design", "Synthetic Biology" and "Encoding Collective Behavior"!
Learn more about the lab by exploring the website through the pictures below